From the 11th to 13th of December the 4th Connective Cities Dialogue Event took place at Betahaus, Berlin and brought together German and international local stakeholders who are directly connected to the field of local economic development and start-up promotion. For urban socio-economic cooperation, applied research and knowledge work, as well as for the creation of new labour ecosystems or community-based businesses, co-working spaces, incubators and innovation labs are increasingly relevant concepts. They demonstrate new ‘grassroots-driven’ practices of urban coordination, collaboration-centric architecture and technology-based work. The co-creation of socio economic environments following principles of e.g. peer-to-peer commerce and collaborative consumption, is a blooming phenomena that demonstrates the demand for new approaches of life long learning, urban developmen. The objective of the event was to initiate an exchange of good practices from different cities to address questions of relevant framing factors for the creation of an ideal ‘start-up environment’. icebauhaus connected icealex and the incubator “Gründerschmiede” of the University of Applied Sciences in Dresden to set up a cooperation between HTW Dresden, the ice hub network and Egyptian universities from Cairo and Alexandria.